Is there any new prognostic score for peripheral T-cell lymphoma?

Akkurd, D.M.; Şahin, H.H.; Doğan, İ.; Okan, V.

doi:10.1016/j.htct.2022.09.1248

Hematology, Transfusion and Cell Therapy

ISSN: 2531-1379

Hematology, Transfusion and Cell Therapy is a quarterly scientific publication of the Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular (ABHH), Associazione Italo-Brasiliana di Ematologia (AIBE), Eurasian Hematology Oncology Group (EHOG), and Sociedade Brasileira de Oncologia Pediátrica (SOBOPE).

Hematology, Transfusion and Cell Therapy publishes original articles, review articles and case reports covering various areas in the field of hematology and hemotherapy. The journal was previously published, until 2016, as Revista Brasileira de Hematologia e Hemoterapia.

ISSN print: 2531-1379
ISSN online: 2531-1387

Published by Elsevier Editora Ltda, Rio de Janeiro, Brazil.

Consensus of the Brazilian association of hematology, hemotherapy and cellular therapy on patient blood management.

Indexed in:

Web of Science, LILACS, SciELO Brazil, ESCI (Web of Science), Scopus, and PubMed/PMC

Sixty patients (30 male/30 female) with PTCL [anaplastic large-cell lymphoma (ALCL) 18, PTCL not otherwise specified 32 and other 10)]. International Prognostic Index (IPI), Modified Glasgow Prognostic Score (mGPS), Geriatric Nutritional Risk Index (GNRI), The combined index of hemoglobin, albumin, lymphocyte, and platelet (HALP), Platelet to Lymphocyte Ratio (PLR) , Neutrophil to Lymphocyte Ratio (NLR), albumin/globulin ratio(A/G), Prognostic nutritional index(PNI) were calculated as in the original references.

Results

mGPS,GNRI,HALP,PLR,NLR,A/G and PNI have not significance to predict overall survival in patients with peripheral T-cell lymphoma(Table-1).

Conclusions

IPI is still superior from all prognostic scores (mGPS,GNRI,HALP,PLR,NLR,A/G and PNI) to predict overall survival.

Full Text

Variables in the Equation Table-1

	B	SE	Wald	df	Sig.	Exp(B)	95,0% CI for Exp(B)
	B	SE	Wald	df	Sig.	Exp(B)	Lower	Upper
IPI	0,598	0,167	12,75	1	0	1,818	1,31	2,525
mGPS	0,001	0,244	0	1	0,996	1,001	0,621	1,614
GNRI	0,014	0,017	0,738	1	0,39	1,014	0,982	1,048
HALP	0,036	0,275	0,017	1	0,897	0,965	0,563	1,655
PLR	0	0,001	0,166	1	0,684	1	0,998	1,003
NLR	0,035	0,046	0,599	1	0,439	1,036	0,947	1,133
A/G	0,399	0,463	0,74	1	0,389	0,671	0,271	1,663
PNI	0,008	0,014	0,357	1	0,55	0,992	0,965	1,019

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