To compare with IPI the usefulness of new prognostic scores in patients with peripheral T-cell lymphoma (PTCL) from a single institution.
MethodologySixty patients (30 male/30 female) with PTCL [anaplastic large-cell lymphoma (ALCL) 18, PTCL not otherwise specified 32 and other 10)]. International Prognostic Index (IPI), Modified Glasgow Prognostic Score (mGPS), Geriatric Nutritional Risk Index (GNRI), The combined index of hemoglobin, albumin, lymphocyte, and platelet (HALP), Platelet to Lymphocyte Ratio (PLR) , Neutrophil to Lymphocyte Ratio (NLR), albumin/globulin ratio(A/G), Prognostic nutritional index(PNI) were calculated as in the original references.
ResultsmGPS,GNRI,HALP,PLR,NLR,A/G and PNI have not significance to predict overall survival in patients with peripheral T-cell lymphoma(Table-1).
ConclusionsIPI is still superior from all prognostic scores (mGPS,GNRI,HALP,PLR,NLR,A/G and PNI) to predict overall survival.
Variables in the Equation Table-1
| B | SE | Wald | df | Sig. | Exp(B) | 95,0% CI for Exp(B) | ||
|---|---|---|---|---|---|---|---|---|
| Lower | Upper | |||||||
| IPI | 0,598 | 0,167 | 12,75 | 1 | 0 | 1,818 | 1,31 | 2,525 |
| mGPS | 0,001 | 0,244 | 0 | 1 | 0,996 | 1,001 | 0,621 | 1,614 |
| GNRI | 0,014 | 0,017 | 0,738 | 1 | 0,39 | 1,014 | 0,982 | 1,048 |
| HALP | 0,036 | 0,275 | 0,017 | 1 | 0,897 | 0,965 | 0,563 | 1,655 |
| PLR | 0 | 0,001 | 0,166 | 1 | 0,684 | 1 | 0,998 | 1,003 |
| NLR | 0,035 | 0,046 | 0,599 | 1 | 0,439 | 1,036 | 0,947 | 1,133 |
| A/G | 0,399 | 0,463 | 0,74 | 1 | 0,389 | 0,671 | 0,271 | 1,663 |
| PNI | 0,008 | 0,014 | 0,357 | 1 | 0,55 | 0,992 | 0,965 | 1,019 |
