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Vol. 44. Núm. S1.
Páginas S32-S33 (outubro 2022)
Vol. 44. Núm. S1.
Páginas S32-S33 (outubro 2022)
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Is there any new prognostic score for peripheral T-cell lymphoma?
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D.M. Akkurd1, H.H. Şahin2, İ. Doğan3, V. Okan2
1 Mersin City Training and Research Hospital Hematology
2 Gaziantep University Sahinbey Research and Practice Hospital Department of Hematology
3 Gaziantep University Department of Biostatistics
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Objective

To compare with IPI the usefulness of new prognostic scores in patients with peripheral T-cell lymphoma (PTCL) from a single institution.

Methodology

Sixty patients (30 male/30 female) with PTCL [anaplastic large-cell lymphoma (ALCL) 18, PTCL not otherwise specified 32 and other 10)]. International Prognostic Index (IPI), Modified Glasgow Prognostic Score (mGPS), Geriatric Nutritional Risk Index (GNRI), The combined index of hemoglobin, albumin, lymphocyte, and platelet (HALP), Platelet to Lymphocyte Ratio (PLR) , Neutrophil to Lymphocyte Ratio (NLR), albumin/globulin ratio(A/G), Prognostic nutritional index(PNI) were calculated as in the original references.

Results

mGPS,GNRI,HALP,PLR,NLR,A/G and PNI have not significance to predict overall survival in patients with peripheral T-cell lymphoma(Table-1).

Conclusions

IPI is still superior from all prognostic scores (mGPS,GNRI,HALP,PLR,NLR,A/G and PNI) to predict overall survival.

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Variables in the Equation Table-1

BSEWalddfSig.Exp(B)95,0% CI for Exp(B)
Lower  Upper 
IPI  0,598  0,167  12,75  1,818  1,31  2,525 
mGPS  0,001  0,244  0,996  1,001  0,621  1,614 
GNRI  0,014  0,017  0,738  0,39  1,014  0,982  1,048 
HALP  0,036  0,275  0,017  0,897  0,965  0,563  1,655 
PLR  0,001  0,166  0,684  0,998  1,003 
NLR  0,035  0,046  0,599  0,439  1,036  0,947  1,133 
A/G  0,399  0,463  0,74  0,389  0,671  0,271  1,663 
PNI  0,008  0,014  0,357  0,55  0,992  0,965  1,019 

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Hematology, Transfusion and Cell Therapy
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