PREMEDICATION DOES NOT PREVENT CLINICAL ALLERGY OR INACTIVATION OF PEG-ASPARAGINASE IN PEDIATRIC ALL: RESULTS FROM A RANDOMISED TRIAL KadS Silva; DK Cecconello; ECM de Senna; MM Lins; IMQS Magalhães; LM Cristofani; AVL de Sousa; LBP Moreira; MLLC Brito; S Epelman; DER Benincasa; C Rechenmacher; LE Daudt; MB Michalowski;

TOWARD OPTIMIZED TREATMENT: INCIDENCE OF HYPERSENSITIVITY REACTIONS AND INACTIVATIONS IN BRAZILIAN CHILDREN RECEIVING PEG-ASPARAGINASE FOR ACUTE LYMPHOBLASTIC LEUKEMIA KAS Silva; DK Cecconello; ECM Senna; LA Carlotto; LM Cristofani; LBP Moreira; MLLC Brito; C Rechenmacher; LE Daudt; MB Michalowski;

CHARACTERIZATION OF GENETIC VARIANTS ASSOCIATED WITH PEG-ASPARAGINASE-RELATED TOXICITIES IN THE BRAZILIAN PEDIATRIC POPULATION DK Cecconello; KadSS Silva; ECM Senna; LA Carlotto; IMQS Magalhães; MM Lins; AVL de Souza; C Rechenmacher; LE Daudt; MB Michalowski;