IMMUNE SENESCENCE AND EXHAUSTION PHENOTYPE MARKED BY LOSS OF NKG2D AND DNAM-1 NK ACTIVATING SIGNALING AND INCREASED TIM-3 T CD8 CHARACTERIZES ADVANCED MYELOFIBROSIS M Medeiros; IC Arruda; AG de Carvalho; CAB Garcia; LS Binelli; BL Adjafre; PS Scheucher; JLdS Schiavinato; CL Araujo; AS Lima; RL Pacca; LC Palma; LL de Figueiredo Pontes;

IMMUNE MATURATION AND CHECKPOINT DYNAMICS DURING TYROSINE KINASE INHIBITOR DOSE REDUCTION PREDICT RELAPSE RISK IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA UNDERGOING TREATMENT DISCONTINUATION LS Binelli; LC Palma; CAB Garcia; M Medeiros; AG de Carvalho; BL Adjafre; LO Marani; PS Scheucher; JLS Schiavinato; PMM Garibaldi; RL Pacca; FS Seguro; RS Tavares; LL Almeida; RS Welner; KBB Pagnano; LL de Figueiredo-Pontes;

FLT3-ITD MUTATION PROMOTES LEUKEMIC DIFFERENTIATION TOWARDS AN IMMATURE CYTOTOXIC STAGE AG de Carvalho; M Medeiros; CAB Garcia; LS Binelli; AFO Costa; BL Adjafre; LO Marani; PS Scheucher; JLS Schiavinato; MIA Madeira; JA de Paula; KBB Pagnano; BKL Duarte; ABF Glória; EC Nunes; M Higashi; WFS Junior; F Traina; EM Rego; LL de Figueiredo-Pontes;