TWELVE-MONTH INTERIM ANALYSIS OF EFFICACY AND SAFETY OF GIVOSIRAN, AN INVESTIGATIONAL RNAI THERAPEUTIC FOR ACUTE HEPATIC PORPHYRIA, IN THE ENVISION OPEN LABEL EXTENSION R. Marchi; L. Duarte; S. E; B. M; R. Dc; S. P; S. U; A.P. P; B. Dm; E. Al; K. S; P. C; P. Jd;