Laboratory hematological tests are widely used in clinical practice to assess health and disease conditions. Although, the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) and the Clinical and Laboratory Standards Institute (CLSI) recommended that reference ranges should be established for each region , to the best of our knowledge, no study has described the reference values of routine hematological parameters in healthy Saudi adults.

To provide reference values of routine hematological parameters in Saudi adults according to age and gender.

Material and Methods: A total of 827 adults potentially healthy Saudi participants with age ranging from 15 to 65 years were enrolled in this cross-sectional study from the central province of Saudi Arabia, Riyadh city.

The reference values of routine hematological parameters (full blood count, hemostatic profile, and biochemical tests of serum hematinic) according to gender were provided in detail (mean, SD, range, median, upper and lower limits) after exclusion of 157 due to various reasons. No difference in any hematological values were observed in relation to age. Current study hematological parameters’ reference ranges were mostly different to the universal established ranges.

This novel study provides the reference ranges of routine hematologic parameters for adult Saudi population for accurate assessments and appropriate management of routine clinical care, hence, to improve quality in health care.