NEXT-GENERATION GENOMIC MONITORING REVEAL A NOVEL RUNX1 PATHOGENIC MUTATION ASSOCIATED WITH TRISOMY 4 AS A SOLE ABNORMALITY IN A YOUNG ADULT WITH ACUTE MYELOID LEUKEMIA
RRC Matosa,b, MM Rochaa, AF Figueiredoc, MG Landd, AH Melgaçoa, JM Souzae, TF Padilhaa, E Abdelhaya,b, GM Ferreiraf, MLM Silvaa,b
a Instituto Nacional do Câncer José de Alencar Gomes da Silva (INCA), Rio de Janeiro, RJ, Brazil
b Postgraduate Program in Oncology, Instituto Nacional do Câncer (INCA), Rio de Janeiro, RJ, Brazil
c Laboratório de Genética, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil
d Internal Medicine Post-Graduation Program of Faculty of Medicine, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil
e Hospital Universitário Pedro Ernesto (HUPE), Rio de Janeiro, RJ, Brazil
f Pediatric Oncohematology Center, Hospital Oswaldo Cruz, Graduate Program, Faculty of Medical Sciences, Instituto de Ciências Biológicas, Universidade de Pernambuco, Recife, PE, Brazil
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