SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION AS CENTRAL NERVOUS SYSTEM LYMPHOMA RELAPSE SIGN OF NODAL DIFFUSE LARGE B-CELL LYMPHOMA

İbili Çetinkaya, Nur Seda; Hasanzade, Ulviya; Alagöz, Gülşah; Karakaya, Nur Rana; Ağzada, Nigar; Babüroğlu, Mehmet; Beşışık, Sevgi

doi:10.1016/j.htct.2023.09.063

Hematology, Transfusion and Cell Therapy

ISSN: 2531-1379

Hematology, Transfusion and Cell Therapy is a quarterly scientific publication of the Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular (ABHH), Associazione Italo-Brasiliana di Ematologia (AIBE), Eurasian Hematology Oncology Group (EHOG), and Sociedade Brasileira de Oncologia Pediátrica (SOBOPE).

Hematology, Transfusion and Cell Therapy publishes original articles, review articles and case reports covering various areas in the field of hematology and hemotherapy. The journal was previously published, until 2016, as Revista Brasileira de Hematologia e Hemoterapia.

ISSN print: 2531-1379
ISSN online: 2531-1387

Published by Elsevier Editora Ltda, Rio de Janeiro, Brazil.

Consensus of the Brazilian association of hematology, hemotherapy and cellular therapy on patient blood management.

Indexed in:

Web of Science, LILACS, SciELO Brazil, ESCI (Web of Science), Scopus, and PubMed/PMC

A woman (65) with nodal diffuse large B-cell lymphoma in remission developed confusion and communication loss before the 6th chemotherapy. She had no fever and no meningeal sign.Biochemistry revealed hyponatremia consistent with the secretion of inappropriate ADH.MRI showed contrast enhancement on the mesencephalic aqueductus cerebri and on 3rd ventricle.Cerebrospinal fluid had low glucose, high protein, and lymphocytes. Central nervous system lymphoma with SIADH as a relapse sign was diagnosed.

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