TOWARD OPTIMIZED TREATMENT: INCIDENCE OF HYPERSENSITIVITY REACTIONS AND INACTIVATIONS IN BRAZILIAN CHILDREN RECEIVING PEG-ASPARAGINASE FOR ACUTE LYMPHOBLASTIC LEUKEMIA
KAS Silvaa,b,c, DK Cecconelloa,b, ECM Sennad, LA Carlottoa, LM Cristofanie, LBP Moreiraf, MLLC Britog, C Rechenmacherb, LE Daudta,b, MB Michalowskia,b
a Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil
b Laboratório de Pediatria Translacional, Centro de Pesquisa Experimental, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil
c Hospital da Criança Conceição, Porto Alegre, Brazil
d Universidade de São Paulo (USP), São Paulo, Brazil
e Instituto de Tratamento do Câncer Infantil (ITACI), Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, Brazil
f Fundação Doutor Amaral Carvalho, Jaú, Brazil
g Hospital Erasto Gaertner (HEG), Curitiba, PR, Brazil
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