We describe a five-year-old girl with high risk B precursor acute lymphoblastic leukemia with central nervous system involvement. Laboratory tests suggested the presence of central hypothyroidism (thyroid-stimulating hormone [TSH]: 0.30 mU/ml, normal range 0.64–6.27 mU/ml; serum free thyroxine [FT4]: 0.70 ng/dl, normal range 0.86–1.4 ng/dl). Magnetic resonance imaging detected heterogeneous contrast enhancement of pituitary gland in addition to cerebral and cerebellar atrophy.
Journal Information
Vol. 43. Issue S3.
Pages S59 (November 2021)
Vol. 43. Issue S3.
Pages S59 (November 2021)
PP 70
Open Access
CENTRAL HYPOTHROIDISM DUE TO ACUTE LYMPHOBLASTIC LEUKEMIA WITH CENTRAL NERVOUS SYSTEM INFILTRATION
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Dilek Kaçar, Seda Şahin, Fatma Burçin Kurtipek, Neşe Yaralı
Ankara City Hospital, Department of Pediatric Hematology and Oncology
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