Elsevier

The Lancet

Volume 333, Issue 8637, 11 March 1989, Pages 514-517
The Lancet

RATES OF THROMBOEMBOLISM WITH THREE DIFFERENT MECHANICAL HEART VALVE PROSTHESES: RANDOMISED STUDY

https://doi.org/10.1016/S0140-6736(89)90065-2Get rights and content

Abstract

In 434 operations for valvular heart disease, patients were randomised to receive Björk-Shiley, Edwards-Duromedics, or Medtronic-Hall mechanical prostheses. At a median follow-up time of 37·5 months there were no differences in hazard of death or non-embolic events. In the first six postoperative months the incidence of thromboembolism was about the same for the three valves. Subsequently, however, the incidence of thromboembolism for the Edwards-Duromedics valve was 3·9 times higher than for the Björk-Shiley valve, and for the Medtronic-Hall valve 2·6 times higher than for the BjörkShiley valve.

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