March 2026 | Hematology, Transfusion and Cell Therapy

CANCERTHERA – 2026

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106272

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MODEL SELECTION OF TUMOR GROWTH DYNAMICS IN UNTREATED MELANOMA AS A BASE LINEAR FOR CAR-T CELLS THERAPY

Nicolly Baptista Alves, Paulo Fernando de Arruda Mancera, Guilherme Rodrigues, Maria Eliza Antunes

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106273

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PREDICTING COMBINED RADIOTHERAPY-IMMUNOTHERAPY OUTCOMES IN MURINE TNBC VIA BAYESIAN CALIBRATION OF BIOLOGY-BASED ODE MODELS AND [89ZR]-CD8 PET IMAGE

Guilherme Rodrigues, Paulo Fernando de Arruda Mancera, Anna G. Sorace, Patrick N. Song, Thomas E. Yankeelov, Ernesto A.B.F. Lima

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106274

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CT-DERIVED BODY COMPOSITION AND MACHINE LEARNING FOR PROGNOSTIC IMPROVEMENT IN COLORECTAL CANCER

Pedro Henrique Alves, Vinicius Barbosa Bassete, Jun Takahashi, Maria Carolina Santos Mendes, José Barreto Campello Carvalheira

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106275

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ASSOCIATIONS OF FEEDING ROUTE, SYSTEMIC INFLAMMATORY CHANGES, AND IL6 GENETIC VARIANT WITH TREATMENT-RELATED WEIGHT LOSS IN LOCALLY ADVANCED HEAD AND NECK CANCER

Richard Silva de Sousa, Daniel Paixão Pequeno, Juliana Carron, Carmen Silvia Passos Lima, Gustavo Jacob Lourenço

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106276

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ASSOCIATION BETWEEN DEPRESSIVE SYMPTOMS AND THE SYSTEMIC IMMUNE-INFLAMMATION INDEX IN PATIENTS WITH LOCALLY ADVANCED HEAD AND NECK CANCER

Angélica Christiny Ribeiro de Toledo, Daniel Paixão Pequeno, Carmen Silvia Passos Lima, Gustavo Jacob Lourenço

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106277

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STRUCTURALLY MODIFIED IKAV PEPTIDES AS BIOLOGICALLY ACTIVE LIGANDS IN TRIPLE-NEGATIVE BREAST CANCER

André Vinicius Zolesi, Danielle Vieira Sobral, Flávio Lopes Alves, Fernanda Ferreira Mendonça, Luciana Malavolta, Leonardo Lima Fuscaldi

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106278

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SYNTHESIS, CHARACTERIZATION AND ANTIPROLIFERATIVE ACTIVITIES OVER MELANOMA (SK-MEL-28) CELLS OF A NOVEL CO(II) COMPLEX WITH A NUCLEOBASE ANALOG

Lucas Zanoni Davoli, Pedro Paulo Corbi, Leticia Pires de Oliveira, Carmen Silvia Passos Lima, Gilberto Carlos Franchi Júnior, Gabriele Pereira Menezes

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106279

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PRELIMINARY MIRNA PROFILING IN ERP29-SILENCED TONGUE SQUAMOUS CELL CARCINOMA HIGHLIGHTS CANCER-RELATED PATHWAYS

Bianca Piovesan Melchiori Peruzza, Carmen Silvia Passos Lima, Juliana Carron, Gustavo Jacob Lourenço

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106280

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ASSESSMENT OF CYTOTOXICITY AND PROTEIN CORONA FORMATION OF Β-NALNF₄ NANOPARTICLES IN RED BLOOD CELLS

Letícia Cerqueira Vasconcelos, Rafael Vieira Perrella, Mateus Pereira Teles, Gabriela Helena da Silva, Jennifer de Pontes Medrades, Ítalo Odone Mazali, Diego Stéfani Teodoro Martinez, Fernando Sigoli

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106281

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PRELIMINARY STUDY OF RADIOLABELING OF ANTI-EGFR PEPTIDE USING THE NOVEL CHELATOR VIA THE TECHNETIUM-99M PERTECHNETATE ROUTE

Aline Morais de Souza, Leonardo Yumoto Carvalheira, Victor Maia Miranda, Fabio Luiz Navarro Marques, Victor Marcelo Deflon, Luciana Malavolta

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106282

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RADIOLABELING OF THE DOTA-C6-ANTI-EGFR PEPTIDE WITH GALLIUM-68: A PRELIMINARY STUDY OF SYNTHESIS, COMPLEXATION, AND RADIOCHEMICAL STABILITY

Aline Morais de Souza, Leonardo Yumoto Carvalheira, Caiubi Rodrigues de Paula Santos, Marycel Rosa Felisa Figols de Barboza, Leonardo Lima Fuscaldi, Luciana Malavolta

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106283

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IN VITRO AND EX VIVO EVALUATION OF 99MTC-LABELED LAMININ-111–DERIVED PEPTIDES FOR BREAST CANCER TARGETING

Fernanda Ferreira Mendonça, Marycel Figols de Barboza, Jorge Mejia Cabeza, Caiubi Rodrigues de Paula Santos, Leonardo Lima Fuscaldi, Luciana Malavolta

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106284

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NT157 MODULATES ONCOGENIC SIGNALLING AND IMPAIRS PROLIFERATION IN PANCREATIC CANCER CELLS

Karina Mitiko Umezu Akiyama, Natália Sudan Parducci, João Agostinho Machado Neto

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106285

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SYNTHESIS AND EVALUATION OF POTENTIAL PEPTIDE INHIBITORS IN MDA-MB-231 BREAST CANCER CELL LINE

Felipe Barbieri Gabrielli, Fernanda Ferreira Mendonça, Danielle Vieira Sobral, Caiubi Rodrigues de Paula Santos, Marycel Rosa Felisa Figols de Barboza, Leonardo Lima Fuscaldi, Luciana Malavolta

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106286

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SYNTHESIS AND GALLIUM-68 RADIOLABELING OF A PEPTIDE FOR THE DETECTION OF AMYLOID FIBRILS IN ALZHEIMER’S DISEASE

Carlos Eduardo Monforte de Oliveira, Fernanda Ferreira Mendonça, Danielle Vieira Sobral, Aline Morais de Souza, Caiubi Rodrigues de Paula Santos, Marycel Rosa Felisa Figols de Barboza, Leonardo Lima Fuscaldi, Luciana Malavolta

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106287

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GOLD(I) COMPLEX AUDMAP PROMOTES APOPTOTIC RESPONSES AND INHIBITS PROLIFERATION AND MIGRATION IN SK-MEL-28 HUMAN MELANOMA CELLS

Isabela Carvalho Diniz, Fernanda Van Petten Vasconcelos Azevedo, Ericka Francislaine Dias Costa, Jennyfer Castro da Silva, Camilla Abbehausen, Carmen Silvia Passos Lima

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106288

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DEVELOPMENT OF A NEW TRIVALENT CHELATING AGENT AND STUDY OF ITS COMPLEXATION TO FORM A COMPLEX WITH OXORRHENIUM(V)

Julia Pontes Gomes, Victor Marcelo Deflon

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106289

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EVALUATION OF THE EXPRESSION OF TRANSPOSABLE ELEMENTS AS BREAST CANCER BIOMARKERS

Letícia de Miranda, Lucas Bicev Alencar, Luciana Rodrigues Carvalho Barros, Roger Chammas

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106290

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NANOENCAPSULATION OF THE GOLD(I) COMPLEX AUMTZ IN LIPID CARRIERS IMPROVES SELECTIVITY AND ANTITUMOR ACTIVITY IN CUTANEOUS SQUAMOUS CELL CARCINOMA MODELS

Fernanda Van Petten Vasconcelos Azevedo, Gabriela Geronimo, Camilla Abbehausen, Eneida de Paula, Carolina Coli Zuliani, Carmen Silvia Passos Lima

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106291

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OPTIMIZED RADIOLABELING OF PSMA-617 WITH ¹⁶¹TB FOR PRECLINICAL APPLICATIONS

Javier Giglio, Kevin Zirbesegger, Juan Vazquez, Eduardo Savio

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106292

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KIF13B C.3163G>A VARIANT IN OROPHARYNGEAL SQUAMOUS CELL CARCINOMA: ASSOCIATIONS WITH RISK AND CLINICAL OUTCOMES

Ericka Francislaine Dias Costa, Gustavo Jacob Lourenço, Carmen Silvia Passos Lima

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106293

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A NOVEL TETRAVALENT AND POLYDENTATE MULTIFUNCTIONAL LIGAND WITH POTENTIAL FOR GALLIUM-67 UPTAKE: SYNTHESIS AND CHARACTERIZATION

Mariana Almeida Figueira, Victor Marcelo Deflon

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106294

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DEVELOPMENT OF A BIFUNCTIONAL CHELATOR FOR GALLIUM AIMING FOR THERANOSTIC APPLICATION IN NUCLEAR MEDICINE

Joaldo Garcia Arruda, Fabio Luiz Navarro Marques, Célia M.C. Fernandez, António R. Paulo, Victor Marcelo Deflon

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106295

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ROBUST AND RIGOROUS IC50 DETERMINATION FOR PRECLINICAL DRUG DISCOVERY

Letícia Fernanda Alves, Gilberto Carlos Franchi Júnior, Alessandra Rodrigues Cardoso Padovam, Leticia Pires de Oliveira, Pedro Paulo Corbi, Carmen Silvia Passos Lima, Diego Samuel Rodrigues

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106296

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EGFR-TARGETING GE11-DERIVED PEPTIDE DIFFERENTIALLY MODULATES TRIPLE-NEGATIVE BREAST CANCER AND GLIOBLASTOMA CELL PROLIFERATION IN VITRO

Julia Naomi Ono, Danielle Vieira Sobral, Fernanda Ferreira Mendonça, Luciana Malavolta, Leonardo Lima Fuscaldi

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106297

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EFFECT OF XPC C.2815A>C VARIANT ON CELL CYCLE–RELATED GENE EXPRESSION IN OROPHARYNGEAL SQUAMOUS CELL CARCINOMA

Quézia Nascimento Martins Alves, Ericka Francislaine Dias Costa, Gustavo Jacob Lourenço, Carmen Silvia Passos Lima

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106298

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TARGETING EGFR WITH THE PEPTIDE LARLLT: IN VITRO EFFECTS ON TRIPLE-NEGATIVE BREAST CANCER AND GLIOBLASTOMA CELLS

Lucas Tetsuya Oyagawa, Danielle Vieira Sobral, Fernanda Ferreira Mendonça, Flávio Lopes Alves, Luciana Malavolta, Leonardo Lima Fuscaldi

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106299

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GROUP 10 THIOSEMICARBAZONE METAL COMPLEXES AS AN ANTIPROLIFERATIVE PLATFORM FOR HEAD AND NECK SQUAMOUS CELL CARCINOMA

Victor Maia Miranda, Fernanda Van Petten Vasconcelos Azevedo, Joaldo Garcia Arruda, Hirya Costa Schibelsky, Daniele Daiane Affonso, Carmen Silvia Passos Lima, Victor Marcelo Deflon

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106300

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PRELIMINARY EVALUATION OF CIRCULATING ERP29 CHAPERONE TRANSCRIPTS IN EXOSOMES FROM PATIENTS WITH HEAD AND NECK CANCER

Rodrigo Costa Cespedes, Carmen Silvia Passos Lima, Gustavo Jacob Lourenço

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106301

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PREPARATION OF FITC FUNCTIONALIZED CELLULOSE NANOFIBRILS FOR FURTHER IN VITRO TUMOR UPTAKE STUDIES

Victória Martins Alves, Mara De Souza Junqueira, Juliana da Silva, Bernardes, Aryel Heitor Ferreira, Fabio Luiz Navarro Marques

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106302

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CANNABIDIOL NANOFORMULATIONS INHIBIT CELL PROLIFERATION AND CANCER-STEM CELL MARKER CD133 IN IN VITRO MODELS OF BURKITT LYMPHOMA.

Helena Alves Freire dos Santos, Paula Vinha, Valéria Barbosa de Souza, Jacqueline Nicolosi, Bruno Roberto Perozzo, Natália Guimarães de Moraes Schenka, André Almeida Schenka

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106303

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PRECLINICAL EVALUATION OF QONA11, A NOVEL QUINAZOLINONE, IN T-CELL ACUTE LYMPHOBLASTIC LEUKAEMIA

Gilberto Carlos Franchi Júnior, Giorgio Antoniolli, Carmen Silvia Passos Lima, Keli Lima, João Agostinho Machado Neto, Euzébio Guimarães Barbosa, Rayssa de Mello Lopes, Tiago Rodrigues, Fernando Antônio Santos Coelho

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106304

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AN AFFORDABLE AND EASY TO IMPLEMENT STRATEGY FOR PRECLINICAL MOLECULAR IMAGING IN THERANOSTICS DEVELOPMENT

Jorge Mejia Cabeza, Michel David Raed, Maria Clara Westmann Anderlini Mattos, Arthur Viana de Laffitte, Orfa Yineth Galvis Alonso, Solange Amorim Nogueira, Lilian Yuri Yamaga, Marycel Rosa Felisa Figols de Barboza, Luciana Malavolta

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106305

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MONTE CARLO SIMULATIONS AS A TOOL FOR DEVELOPING PRE-CLINICAL INSTRUMENTATION

Michel David Raed, Maria Clara Westmann Anderlini Mattos, Arthur Viana de Laffitte, Orfa Yineth Galvis Alonso, Solange Amorim Nogueira, Lilian Yuri Yamaga, Marycel Rosa Felisa Figols de Barboza, Luciana Malavolta, Jorge Mejia Cabeza

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106306

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ANTIPROLIFERATIVE ACTIVITIES OF A SILVER COMPLEX WITH A SCHIFF BASE OVER TUMORAL CELLS

Maria Paula Dias Carneiro Miguel, Leticia Pires de Oliveira, Douglas Hideki Nakahata, Gilberto Carlos Franchi Júnior, Pedro G. Esquezaro, Carmen Silvia Passos Lima, Raphael E.F. de Paiva, Pedro Paulo Corbi

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106307

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IN VITRO EVALUATION OF THE ANTITUMOR ACTIVITY AND CUTANEOUS PERMEABILITY OF A SILVER-BASED METAL DRUG COMBINED WITH A MONOTERPENE FOR SKIN CANCER TREATMENT

Daniele Affonso, Juliana Carron, Gabriele Pereira Menezes, Henrique Vinícius Cerqueira da Silva, João Ernesto Carvalho, Marco Aurélio Zezzi Arruda, Pedro Paulo Corbi, Ana Lucia Tasca Gois Ruiz, Carmen Silvia Passos Lima

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106308

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EVALUATION OF THE DIFFERENCES IN THE ELECTROPHORETIC PROFILE OF COPPER(II) BIS-PHENANTHROLINE COMPLEXES

Francisco Mastrobuono Cordeiro de Almeida, Gabriele Pereira Menezes, Douglas Hideki Nakahata, Pedro Paulo Corbi, Raphael Enoque Ferraz de Paiva, Carmen Silvia Passos Lima, Gilberto Carlos Franchi Júnior

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106309

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A NOVEL ADAMANTANE-DERIVED SULFUR-CONTAINING SCHIFF BASE: SYNTHESIS AND PRELIMINARY BIOLOGICAL STUDIES

Laura Barrosa, Pedro Paulo Corbi, Ana Carolina Gomes Jardim, Júlia Amaral Vieira d’Almeida

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106310

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THE WASHOUT PHENOMENON AS A THERANOSTIC CHALLENGE: A KINETIC ANALYSIS OF 18F-PSMA UPTAKE IN ADVANCED HEPATOCELLULAR CARCINOMA

Giulia Picciola Bordoni, Maria Emilia Seren Takahashi, Fabíola Furtuoso Zarpelão, Najua Abou Arabi Silveira, Victor C.C.R. Heringer, Simone Kuba, Natália Tobar Toledo Prudente da Silva, Sérgio Querino Brunetto, ... Celso Dario Ramos

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106311

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IN SILICO STUDY OF SOME PHARMACOKINETIC AND PHARMACOLOGICAL PROPERTIES OF THREE ANACARDIC ACIDS IN THE CONTEXT OF SKIN DISEASES

Augusto de Souza Silva, Ana Lucia Tasca Gois Ruiz

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106312

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ANTI-INTEGRIN PEPTIDE WITH DOTA CHELATOR RADIOLABELED WITH GA-68 AS A THERANOSTIC AGENT IN GLIOBLASTOMA

Fábio Silva, Juliana Carron, Gabriella Fraiji Melo, Flávio Lopes Alves, Maria Eduarda Oliveira Amaro Santos, Vânia Pereira de Castro Rodrigues, João Ernesto Carvalho, Ana Lucia Tasca Gois Ruiz, ... Carmen Silvia Passos Lima

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106313

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EX VIVO DRUG SCREENING AS A CRITERION FOR PATIENT SELECTION IN CLINICAL TRIALS

Samara de Sousa Mariano, Leandro de Paula Henrique Assis, Juliana Ronchi Correa, Maria Luiza Silva Pires, Aryannny Paula Sousa Ferreira, Manuella Munuera Hoff Rosati, Nathalia Moreno Cury, Adrielli Caroline Soares, ... Jose Andres Yunes

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106314

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RADIOLABELING AND BIODISTRIBUTION OF [⁶⁸GA]GA-FAPI-46 IN A HUMAN NON-SMALL CELL LUNG CANCER XENOGRAFT MODEL

Caiubi Rodrigues de Paula Santos, Luciana Malavolta, Leonardo Lima Fuscaldi, Fernanda Ferreira Mendonça, Danielle Vieira Sobral, Jorge Mejia Cabeza, Michel David Raed, Lilian Yuri Yamaga, ... Marycel Figols de Barboza

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106315

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EVALUATION OF NEW RADIOLABELED ANTI-EGFR PEPTIDE MODIFIED BY BIS(SEMICARBAZONE) METAL CHELATOR AS THERANOSTIC STRATEGY IN COLORECTAL AND HEAD AND NECK CANCERS

Amanda Helena Tejada, Gilberto Carlos Franchi Júnior, Gustavo Jacob Lourenço, Carmen Silvia Passos Lima

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106316

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LIPOSOMAL NANOFORMULATION OF A COPPER-BASED COMPLEX ASSOCIATED WITH PARPI MODULATES ANGIOGENIC PROCESSES IN ENDOTHELIAL CELLS

Gislaine Gonçalves Rocha, Fernanda Cardoso da Silva, Paula Marynella Alves Pereira Lima, Samuel Cota Teixeira, Helen Soares Valença Ferreira, Raoni Pais Siqueira, Lígia Nunes de Morais Ribeiro, Wendell Guerra, ... Thaise Araújo

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106317

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A NOVEL LIPOSOME CONTAINING A SYNERGISTIC COMBINATION OF A COPPER COMPLEX AND A PARP INHIBITOR FOR THE TREATMENT OF TRIPLE-NEGATIVE BREAST CANCER

Paula Marynella Alves Pereira Lima, Lígia Nunes de Morais Ribeiro, Raoni Pais Siqueira, Wendell Guerra, Simone Sommerfeld, Gislaine Gonçalves Rocha, Laryssa Aparecida Sales Barbosa, Belchiolina Beatriz Fonseca, Thaise Gonçalves Araújo

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106318

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COMBINATION OF PACLITAXEL AND A COPPER (II) COMPLEX AS A SYNERGISTIC STRATEGY FOR THE TREATMENT OF TRIPLE-NEGATIVE BREAST CANCER

Laryssa Aparecida Sales Barbosa, Paula Marynella Alves Pereira Lima, Douglas Cardoso Brandão, Janaína do Couto Almeida, Gislaine Gonçalves Rocha, Henrique Gabriel Rodrigues Alves, Wendell Guerra, Thaise Gonçalves Araújo

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106319

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BIOLOGICAL ASSESSMENT OF [¹⁶¹TB]TB-PSMA IN HUMAN PROSTATE CANCER CELL LINES

Rosina Dapueto, Manuela Bentura, Florencia Arredondo, Juan Vazquez, Kevin Zirbesegger, Javier Giglio, Eduardo Savio

Hematol Transfus Cell Ther. 2026;48 Supl 1: 106320

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